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LIBGEN documentation |
# Gribskov Protein Profile # Columns are amino acids A->Z # Last column is indel penalty # Rows are alignment positions 1->n Gribskov Name ./54894.disc Matrix pprofile Length 97 Max_score 1073.49 Threshold 75 Gap_open 3.00 Gap_extend 0.30 Consensus GVEAIKNGTVIDHIPAGRAQIGFKLLGLFKLTETDQRITIGLNLPSSGELGRKDLIKIENTFISEDQADQLALYAPQATVNRIDNYEVVEKSRLSLP 2.40 0.00 0.80 2.40 2.00 -2.40 6.00 -0.80 -1.20 0.00 -0.40 -2.00 -1.20 1.60 0.00 1.20 0.80 -1.20 2.40 1.60 0.00 0.80 -4.00 0.00 -2.40 0.00 3.49 3.49 2.00 0.00 2.00 -2.00 -2.00 2.00 2.00 -3.00 11.00 0.00 -2.00 8.00 6.00 -3.00 0.00 1.00 -2.00 -3.00 -1.00 2.00 0.00 15.00 -8.00 0.00 -1.00 0.00 4.55 4.55 2.00 0.00 -3.00 6.40 9.40 -5.20 3.60 3.00 -2.00 0.00 3.80 -3.40 -1.40 3.80 0.00 2.00 4.20 3.20 4.40 1.60 0.00 -2.00 -3.40 0.00 -5.00 0.00 4.55 4.55 9.00 0.00 -0.60 3.00 3.00 -5.40 3.20 -0.20 -0.80 0.00 6.00 -1.80 0.80 2.80 0.00 3.40 2.80 1.40 3.20 3.20 0.00 0.40 -4.40 0.00 -4.20 0.00 4.55 4.55 0.00 0.00 2.00 -2.00 -2.00 6.00 -3.00 -3.00 15.00 0.00 -2.00 8.00 6.00 -3.00 0.00 -2.00 -3.00 -3.00 -1.00 2.00 0.00 11.00 -5.00 0.00 1.00 0.00 4.55 4.55 -1.20 0.00 -4.80 1.80 1.80 -5.60 -1.80 2.60 -2.40 0.00 12.20 -3.40 2.00 2.80 0.00 1.80 4.00 10.80 1.60 0.80 0.00 -2.40 5.80 0.00 -6.00 0.00 4.55 4.55 0.40 0.00 -1.20 2.80 2.40 -4.60 1.60 3.60 -2.60 0.00 5.20 -4.00 -1.00 7.00 0.00 2.00 3.00 6.60 4.60 1.00 0.00 -2.60 4.60 0.00 -3.60 0.00 4.55 4.55 6.00 0.00 2.00 6.00 5.00 -6.00 15.00 -2.00 -3.00 0.00 -1.00 -5.00 -3.00 4.00 0.00 3.00 2.00 -3.00 6.00 4.00 0.00 2.00 -10.00 0.00 -6.00 0.00 4.55 4.55 3.60 0.00 2.00 1.20 1.20 -2.00 3.60 -1.40 3.80 0.00 1.20 0.80 1.20 1.00 0.00 2.60 -1.20 -1.40 2.20 12.40 0.00 4.60 -6.40 0.00 -2.60 0.00 4.55 4.55 2.00 0.00 2.00 -2.00 -2.00 2.00 2.00 -3.00 11.00 0.00 -2.00 8.00 6.00 -3.00 0.00 1.00 -2.00 -3.00 -1.00 2.00 0.00 15.00 -8.00 0.00 -1.00 0.00 4.55 4.55 0.00 0.00 2.00 -2.00 -2.00 6.00 -3.00 -3.00 15.00 0.00 -2.00 8.00 6.00 -3.00 0.00 -2.00 -3.00 -3.00 -1.00 2.00 0.00 11.00 -5.00 0.00 1.00 0.00 4.55 4.55 3.00 0.00 -5.00 15.00 10.00 -10.00 6.00 4.00 -2.00 0.00 3.00 -5.00 -4.00 6.00 0.00 1.00 6.00 0.00 2.00 2.00 0.00 -2.00 -11.00 0.00 -5.00 0.00 4.55 4.55 -1.00 0.00 -1.00 4.00 4.00 -1.00 -2.00 15.00 -3.00 0.00 1.00 -2.00 -3.00 5.00 0.00 2.00 6.00 5.00 -2.00 -1.00 0.00 -3.00 -1.00 0.00 3.00 0.00 4.55 4.55 0.00 0.00 2.00 -2.00 -2.00 6.00 -3.00 -3.00 15.00 0.00 -2.00 8.00 6.00 -3.00 0.00 -2.00 -3.00 -3.00 -1.00 2.00 0.00 11.00 -5.00 0.00 1.00 0.00 4.55 4.55 5.00 0.00 1.00 1.00 1.00 -6.00 3.00 2.00 -2.00 0.00 1.00 -3.00 -2.00 0.00 0.00 15.00 3.00 3.00 4.00 3.00 0.00 1.00 -8.00 0.00 -8.00 0.00 4.55 4.55 4.00 0.00 0.80 0.80 0.80 -2.20 1.80 0.20 -0.40 0.00 0.20 -0.80 -0.40 0.40 0.00 4.00 1.00 0.00 1.60 1.40 0.00 0.60 -3.20 0.00 -2.20 0.00 2.38 2.38 2.40 0.00 0.80 2.40 2.00 -2.40 6.00 -0.80 -1.20 0.00 -0.40 -2.00 -1.20 1.60 0.00 1.20 0.80 -1.20 2.40 1.60 0.00 0.80 -4.00 0.00 -2.40 0.00 2.38 2.38 -1.20 0.00 -1.20 0.00 0.00 -2.00 -1.20 2.00 -1.20 0.00 3.20 -1.60 0.80 0.40 0.00 1.20 1.60 6.00 0.40 -0.40 0.00 -1.20 5.20 0.00 -2.40 0.00 2.38 2.38 15.00 0.00 3.00 3.00 3.00 -5.00 6.00 -1.00 0.00 0.00 0.00 -1.00 0.00 2.00 0.00 5.00 2.00 -3.00 4.00 4.00 0.00 2.00 -8.00 0.00 -3.00 0.00 4.55 4.55 -0.40 0.00 -5.40 0.00 1.20 1.00 -1.60 2.00 1.20 0.00 2.80 4.40 3.80 0.60 0.00 -0.40 5.00 1.40 -1.40 -0.80 0.00 0.80 1.60 0.00 -0.40 0.00 4.55 4.55 4.20 0.00 2.20 -0.20 -0.20 1.20 1.20 -2.20 8.60 0.00 -0.80 4.40 3.60 -1.00 0.00 1.00 -1.40 -2.60 0.80 5.00 0.00 8.20 -6.40 0.00 -1.00 0.00 4.55 4.55 4.00 0.00 0.40 2.40 2.20 -2.20 8.80 -2.40 1.60 0.00 -0.60 1.00 2.40 1.20 0.00 1.60 0.80 -2.00 2.80 2.80 0.00 5.40 -8.20 0.00 -4.00 0.00 4.55 4.55 -2.40 0.00 -3.20 -6.40 -4.00 12.00 -5.00 -1.80 8.60 0.00 -4.00 12.40 8.00 -4.20 0.00 -4.00 -4.20 -4.20 -3.00 -1.20 0.00 6.20 5.80 0.00 6.60 0.00 4.55 4.55 -0.60 0.00 -5.40 2.40 2.40 -5.80 -1.40 1.80 -2.20 0.00 13.60 -3.20 2.00 3.40 0.00 1.40 4.00 9.40 1.80 1.40 0.00 -2.20 3.40 0.00 -6.00 0.00 4.55 4.55 3.00 0.00 -1.80 -2.20 -1.40 5.40 -1.00 -2.20 8.40 0.00 -2.00 9.00 7.20 -2.40 0.00 -0.40 -1.00 -3.40 -1.20 1.20 0.00 8.80 -2.20 0.00 0.60 0.00 4.55 4.55 -1.00 0.00 -8.00 -5.00 -3.00 12.00 -5.00 -2.00 8.00 0.00 -3.00 15.00 12.00 -4.00 0.00 -3.00 -1.00 -4.00 -4.00 -1.00 0.00 8.00 5.00 0.00 3.00 0.00 4.55 4.55 4.00 0.00 2.00 3.80 3.40 -4.80 8.20 -1.40 -2.00 0.00 3.40 -4.20 -2.00 3.60 0.00 3.00 1.20 0.80 8.80 3.20 0.00 0.00 -2.60 0.00 -5.20 0.00 4.55 4.55 -0.80 0.00 -6.00 -4.40 -2.80 10.80 -4.60 -2.20 9.40 0.00 -2.80 13.60 10.80 -3.80 0.00 -2.80 -1.40 -3.80 -3.40 -0.40 0.00 8.60 3.00 0.00 2.60 0.00 4.55 4.55 -3.80 0.00 -2.80 -7.00 -4.20 10.40 -5.20 0.00 4.60 0.00 -2.60 9.40 5.80 -3.60 0.00 -3.60 -4.20 -0.80 -2.40 -2.20 0.00 2.20 10.80 0.00 7.20 0.00 4.55 4.55 2.80 0.00 -2.80 5.60 4.40 -6.80 4.40 1.20 -2.20 0.00 6.60 -3.80 -1.00 3.60 0.00 4.20 3.80 3.20 3.20 2.60 0.00 -0.60 -5.40 0.00 -6.20 0.00 4.55 4.55 0.60 0.00 -4.20 -2.60 -1.40 4.60 -2.00 -1.00 4.00 0.00 -0.60 7.80 7.40 -2.20 0.00 1.40 0.20 -0.60 -1.40 0.20 0.00 4.60 -0.20 0.00 -0.60 0.00 2.83 2.83 0.80 0.00 0.00 1.60 1.60 -2.40 0.60 3.60 -0.40 0.00 2.60 -1.60 -0.20 2.00 0.00 2.20 1.60 3.60 1.00 5.60 0.00 -0.40 0.00 0.00 -1.80 0.00 2.83 2.83 3.60 0.00 -1.40 6.80 8.40 -5.20 7.00 1.80 -2.20 0.00 2.20 -3.80 -2.60 6.40 0.00 1.80 3.40 -0.20 5.60 2.60 0.00 -1.20 -6.40 0.00 -4.20 0.00 4.55 4.55 2.40 0.00 2.80 2.20 3.20 -0.40 2.60 0.60 0.40 0.00 0.60 -1.20 -1.20 2.20 0.00 0.60 -0.60 -1.40 3.80 6.40 0.00 -0.00 -1.80 0.00 0.00 0.00 4.55 4.55 4.80 0.00 -1.60 7.80 5.60 -7.20 6.00 2.00 -2.00 0.00 2.60 -4.00 -1.80 3.80 0.00 2.60 4.00 1.80 3.00 2.20 0.00 -0.60 -5.40 0.00 -5.00 0.00 4.55 4.55 -1.00 0.00 -4.00 0.40 0.40 0.20 -2.00 4.00 -2.60 0.00 1.40 1.00 -0.80 1.60 0.00 -1.40 6.80 3.80 -0.80 -2.40 0.00 -3.00 2.20 0.00 1.60 0.00 4.55 4.55 -3.00 0.00 -3.00 0.00 0.00 -5.00 -3.00 5.00 -3.00 0.00 8.00 -4.00 2.00 1.00 0.00 3.00 4.00 15.00 1.00 -1.00 0.00 -3.00 13.00 0.00 -6.00 0.00 4.55 4.55 [Part of this file has been deleted for brevity] 3.60 0.00 2.80 3.00 2.80 -4.20 6.40 -1.40 -1.60 0.00 4.00 -4.00 -2.00 3.40 0.00 3.20 0.60 1.60 10.60 3.00 0.00 -0.60 0.00 0.00 -4.80 0.00 4.55 4.55 1.20 0.00 0.40 1.20 1.00 -1.20 3.00 -0.40 -0.60 0.00 -0.20 -1.00 -0.60 0.80 0.00 0.60 0.40 -0.60 1.20 0.80 0.00 0.40 -2.00 0.00 -1.20 0.00 3.49 3.49 4.20 0.00 -4.20 5.80 7.80 -5.80 2.80 1.80 -1.60 0.00 7.20 -2.60 0.00 4.00 0.00 1.80 4.40 2.60 2.40 2.40 0.00 -1.20 -5.60 0.00 -5.00 0.00 4.55 4.55 -0.40 0.00 -5.20 -4.00 -2.40 8.00 -3.80 -2.60 8.60 0.00 -0.80 12.40 12.00 -3.40 0.00 -2.40 -1.00 -1.40 -3.00 0.00 0.00 7.80 -0.20 0.00 1.00 0.00 4.55 4.55 6.00 0.00 2.00 6.00 5.00 -6.00 15.00 -2.00 -3.00 0.00 -1.00 -5.00 -3.00 4.00 0.00 3.00 2.00 -3.00 6.00 4.00 0.00 2.00 -10.00 0.00 -6.00 0.00 4.55 4.55 -1.60 0.00 -1.20 0.40 0.40 -4.60 -1.20 3.60 -2.60 0.00 6.80 -4.00 1.00 1.40 0.00 3.20 3.00 12.20 3.80 -0.20 0.00 -2.60 11.00 0.00 -5.60 0.00 4.55 4.55 0.00 0.00 -6.00 3.00 3.00 -6.00 -1.00 1.00 -2.00 0.00 15.00 -3.00 2.00 4.00 0.00 1.00 4.00 8.00 2.00 2.00 0.00 -2.00 1.00 0.00 -6.00 0.00 4.55 4.55 3.00 0.00 -5.00 15.00 10.00 -10.00 6.00 4.00 -2.00 0.00 3.00 -5.00 -4.00 6.00 0.00 1.00 6.00 0.00 2.00 2.00 0.00 -2.00 -11.00 0.00 -5.00 0.00 4.55 4.55 -0.60 0.00 -4.00 -3.80 -2.60 9.60 -4.20 -2.40 10.80 0.00 -2.60 12.20 9.60 -3.60 0.00 -2.60 -1.80 -3.60 -2.80 0.20 0.00 9.20 1.00 0.00 2.20 0.00 4.55 4.55 0.00 0.00 -2.00 -3.20 -2.40 7.60 -2.80 -2.60 11.40 0.00 -2.40 10.80 8.40 -3.40 0.00 -1.80 -2.00 -3.40 -2.20 0.80 0.00 10.60 -1.60 0.00 1.40 0.00 4.55 4.55 0.00 0.00 -6.00 3.00 3.00 -6.00 -1.00 1.00 -2.00 0.00 15.00 -3.00 2.00 4.00 0.00 1.00 4.00 8.00 2.00 2.00 0.00 -2.00 1.00 0.00 -6.00 0.00 4.55 4.55 0.00 0.00 2.00 -2.00 -2.00 6.00 -3.00 -3.00 15.00 0.00 -2.00 8.00 6.00 -3.00 0.00 -2.00 -3.00 -3.00 -1.00 2.00 0.00 11.00 -5.00 0.00 1.00 0.00 4.55 4.55 3.00 0.00 -6.00 10.00 15.00 -6.00 5.00 4.00 -2.00 0.00 3.00 -3.00 -2.00 5.00 0.00 1.00 6.00 0.00 2.00 2.00 0.00 -2.00 -11.00 0.00 -5.00 0.00 4.55 4.55 3.00 0.00 -2.40 7.80 6.00 -6.20 6.60 3.40 -2.80 0.00 2.80 -4.40 -3.20 11.00 0.00 0.80 4.00 0.00 3.40 2.40 0.00 -1.80 -6.00 0.00 -2.80 0.00 4.55 4.55 0.80 0.00 2.60 -0.60 -0.60 0.80 0.20 0.60 2.60 0.00 0.80 1.00 1.40 0.20 0.00 0.40 -1.20 0.80 0.40 5.60 0.00 3.00 0.80 0.00 0.40 0.00 4.55 4.55 -2.60 0.00 -1.40 -5.80 -3.40 8.20 -3.40 -1.00 5.40 0.00 -1.00 8.20 4.60 -2.80 0.00 -3.20 -4.40 -2.00 -1.60 -1.00 0.00 3.80 5.80 0.00 6.40 0.00 4.55 4.55 0.60 0.00 -2.20 -2.60 -1.80 6.00 -2.60 -1.60 8.80 0.00 -1.80 8.60 6.80 -2.80 0.00 1.00 -1.00 -2.20 -1.20 1.00 0.00 7.80 -1.60 0.00 0.00 0.00 4.55 4.55 2.40 0.00 2.00 4.20 3.20 -4.80 4.20 0.60 -1.60 0.00 3.40 -4.20 -2.20 3.20 0.00 3.20 1.40 3.60 9.60 2.00 0.00 -1.60 2.20 0.00 -4.60 0.00 4.55 4.55 2.80 0.00 -6.00 9.20 13.20 -6.40 4.40 4.40 -2.20 0.00 3.20 -2.60 -1.60 4.80 0.00 1.40 7.80 0.80 1.40 1.40 0.00 -2.00 -9.80 0.00 -5.20 0.00 4.55 4.55 3.60 0.00 -3.20 7.20 5.20 -7.20 2.80 2.60 -1.80 0.00 5.80 -3.60 -0.80 3.80 0.00 2.20 4.40 4.00 2.20 1.80 0.00 -1.40 -3.20 0.00 -5.00 0.00 4.55 4.55 2.40 0.00 -5.80 8.60 8.60 -8.00 3.40 5.20 -2.60 0.00 3.60 -2.20 -1.20 4.60 0.00 2.20 11.40 2.40 0.20 0.20 0.00 -2.00 -7.40 0.00 -5.60 0.00 4.55 4.55 6.60 0.00 0.40 -0.60 -0.20 1.20 2.20 -2.00 6.00 0.00 -1.40 5.80 4.80 -1.20 0.00 1.80 -0.20 -3.20 0.40 2.20 0.00 8.40 -5.40 0.00 -1.00 0.00 4.55 4.55 3.00 0.00 -2.60 9.60 8.40 -6.80 5.40 3.00 -2.00 0.00 3.00 -4.20 -3.20 7.00 0.00 1.40 4.20 0.40 4.80 2.20 0.00 -2.00 -6.60 0.00 -4.00 0.00 4.55 4.55 1.00 0.00 -4.80 1.60 2.00 -1.60 -0.00 1.60 2.20 0.00 3.60 3.60 4.00 1.00 0.00 1.00 6.20 1.80 -1.00 0.20 0.00 3.40 -2.40 0.00 -3.20 0.00 4.55 4.55 -0.80 0.00 -6.00 -4.40 -2.80 10.80 -4.60 -2.20 9.40 0.00 -2.80 13.60 10.80 -3.80 0.00 -2.80 -1.40 -3.80 -3.40 -0.40 0.00 8.60 3.00 0.00 2.60 0.00 4.55 4.55 11.00 0.00 2.60 3.40 3.20 -4.80 7.40 -1.20 -0.20 0.00 0.20 -1.80 -0.60 2.40 0.00 4.20 1.40 -2.60 4.20 6.20 0.00 2.00 -8.00 0.00 -3.60 0.00 4.55 4.55 -0.80 0.00 -6.00 -4.40 -2.80 10.80 -4.60 -2.20 9.40 0.00 -2.80 13.60 10.80 -3.80 0.00 -2.80 -1.40 -3.80 -3.40 -0.40 0.00 8.60 3.00 0.00 2.60 0.00 4.55 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1.00 0.00 11.60 -3.40 0.00 2.20 0.00 4.55 4.55 2.00 0.00 -3.00 6.00 5.00 -5.00 4.00 5.00 -3.00 0.00 4.00 -4.00 -3.00 15.00 0.00 0.00 4.00 1.00 3.00 2.00 0.00 -3.00 -3.00 0.00 -1.00 0.00 4.55 4.55 -0.40 0.00 -1.60 0.40 0.40 -2.00 -1.00 2.00 3.40 0.00 3.20 1.40 3.20 0.00 0.00 1.60 3.60 5.60 -0.20 0.20 0.00 3.60 1.60 0.00 -3.60 0.00 4.55 4.55 0.00 0.00 2.00 -2.00 -2.00 6.00 -3.00 -3.00 15.00 0.00 -2.00 8.00 6.00 -3.00 0.00 -2.00 -3.00 -3.00 -1.00 2.00 0.00 11.00 -5.00 0.00 1.00 0.00 4.55 4.55 1.80 0.00 -5.00 10.00 10.00 -7.40 3.80 4.20 -2.20 0.00 4.00 -4.00 -2.00 4.60 0.00 1.40 5.60 3.00 1.80 1.40 0.00 -2.20 -6.20 0.00 -5.20 0.00 4.55 4.55 2.40 0.00 -3.80 9.60 7.00 -7.00 4.80 4.60 -2.60 0.00 3.60 -4.40 -3.40 11.40 0.00 0.40 4.80 0.60 2.60 2.00 0.00 -2.60 -6.20 0.00 -2.60 0.00 4.55 4.55 -3.00 0.00 10.00 -5.00 -5.00 13.00 -6.00 3.00 1.00 0.00 -6.00 3.00 -1.00 -1.00 0.00 -8.00 -6.00 -6.00 -4.00 -3.00 0.00 -1.00 11.00 0.00 15.00 0.00 4.55 4.55 2.20 0.00 -4.40 6.20 9.20 -4.40 3.20 2.00 0.60 0.00 4.40 -0.80 0.40 3.20 0.00 1.00 4.00 1.00 1.40 2.00 0.00 1.40 -8.00 0.00 -4.40 0.00 4.55 4.55 2.00 0.00 2.00 -2.00 -2.00 2.00 2.00 -3.00 11.00 0.00 -2.00 8.00 6.00 -3.00 0.00 1.00 -2.00 -3.00 -1.00 2.00 0.00 15.00 -8.00 0.00 -1.00 0.00 4.55 4.55 2.40 0.00 2.00 -1.20 -1.20 1.00 2.40 -2.60 9.20 0.00 -1.20 6.20 4.80 -2.00 0.00 1.40 -1.80 -2.60 -0.20 4.60 0.00 12.40 -7.60 0.00 -1.40 0.00 4.55 4.55 3.60 0.00 -2.80 7.00 8.60 -6.00 7.80 1.00 -2.40 0.00 3.80 -3.80 -1.60 4.40 0.00 1.80 4.00 0.40 3.60 2.80 0.00 -0.40 -8.20 0.00 -5.60 0.00 4.55 4.55 0.00 0.00 -6.00 3.00 3.00 -6.00 -1.00 1.00 -2.00 0.00 15.00 -3.00 2.00 4.00 0.00 1.00 4.00 8.00 2.00 2.00 0.00 -2.00 1.00 0.00 -6.00 0.00 4.55 4.55 1.20 0.00 0.60 -0.60 -0.20 0.60 1.20 -0.80 2.80 0.00 1.40 2.20 2.80 0.00 0.00 1.80 -0.20 2.00 5.20 1.20 0.00 3.60 3.20 0.00 -2.40 0.00 4.55 4.55 1.60 0.00 -2.00 2.00 2.00 -4.40 -0.60 5.00 -2.20 0.00 6.40 -2.80 0.60 2.60 0.00 2.80 4.00 8.00 1.20 0.60 0.00 -1.80 3.60 0.00 -3.60 0.00 4.55 4.55 1.40 0.00 -4.40 -2.60 -1.40 4.80 -1.80 -0.40 4.00 0.00 -1.40 7.80 6.40 -2.40 0.00 4.20 0.60 -1.20 -0.80 0.60 0.00 5.20 -0.20 0.00 -1.40 0.00 4.55 4.55 2.60 0.00 -1.20 4.60 5.60 -5.20 3.60 1.40 -1.80 0.00 5.20 -3.00 -1.20 3.80 0.00 2.60 4.60 2.80 6.60 1.80 0.00 -1.60 -1.80 0.00 -5.00 0.00 4.55 4.55 -0.40 0.00 -6.00 -4.40 -2.80 10.00 -3.60 -2.20 8.60 0.00 -2.80 13.60 10.80 -3.80 0.00 -2.20 -1.20 -3.80 -3.40 -0.40 0.00 9.40 2.40 0.00 2.20 0.00 4.55 4.55 5.00 0.00 1.00 1.00 1.00 -6.00 3.00 2.00 -2.00 0.00 1.00 -3.00 -2.00 0.00 0.00 15.00 3.00 3.00 4.00 3.00 0.00 1.00 -8.00 0.00 -8.00 0.00 4.55 4.55 |
# Gribskov Protein Profile # Columns are amino acids A->Z # Last column is indel penalty # Rows are alignment positions 1->n Gribskov Name ./55074.disc Matrix pprofile Length 257 Max_score 1759.18 Threshold 75 Gap_open 3.00 Gap_extend 0.30 Consensus GVEAIKNGTVIDHIPAGRAQIGFKLLGLFKLTETDQRITIGLNLPSSGELGRKDLIKIENTFISEDQADQLALYAPQATVNRIDNYEVVEKSRLSLPMMFHFRAFKKKKFDDVTILFADIVGFTAICAQCSEGPDELIDMLNELFGRFDELCGEPHYLDCYKIKTIGDAYCCASGLHEKRADHAFCCAEMALKMIEAIEEVMDPDGDALDDSXREFEEQRAEGECEXTPPTAHMDPEVXSMLWENIKMRIGIHSGLSVLAGVLGVRKPRYDLWGNDVNLANKMESGGVAGRIHISEATYRLLSAEDGKDYEVEAGCGDERAGAGAVADPIKGFKILLIPSRNFAALRLDREXFD 0.00 0.00 -1.00 -0.67 -0.33 0.83 -0.50 -0.50 1.00 0.00 0.33 2.00 2.50 -0.50 0.00 -0.33 0.00 0.33 -0.50 0.00 0.00 1.00 -0.50 0.00 -0.17 0.00 1.13 1.13 0.00 0.00 -1.00 -0.67 -0.33 0.83 -0.50 -0.50 1.00 0.00 0.33 2.00 2.50 -0.50 0.00 -0.33 0.00 0.33 -0.50 0.00 0.00 1.00 -0.50 0.00 -0.17 0.00 1.13 1.13 -0.50 0.00 -0.33 -1.00 -0.50 2.67 -0.83 0.17 3.00 0.00 -0.67 2.67 1.33 1.17 0.00 -1.33 -1.17 -1.17 -0.17 0.17 0.00 1.67 0.67 0.00 2.17 0.00 1.13 1.13 0.17 0.00 -0.33 1.33 1.17 -0.00 -0.17 2.83 1.50 0.00 0.50 0.33 0.00 2.83 0.00 0.00 1.17 0.50 0.00 0.50 0.00 0.83 -1.50 0.00 0.50 0.00 1.13 1.13 -0.50 0.00 -1.67 -0.17 0.33 0.67 -0.50 0.83 0.17 0.00 2.17 0.83 0.67 2.33 0.00 -0.83 0.00 0.67 0.33 0.17 0.00 -0.50 1.67 0.00 1.00 0.00 1.13 1.13 -1.00 0.00 -0.67 -0.33 -0.33 -0.67 -1.50 1.17 1.50 0.00 2.33 0.00 1.67 -0.17 0.00 0.67 0.83 4.50 0.17 0.00 0.00 0.83 3.50 0.00 -1.83 0.00 1.13 1.13 2.83 0.00 2.33 -0.17 -0.17 0.33 0.50 0.67 -0.17 0.00 -0.83 -0.17 -0.50 0.17 0.00 2.00 -0.17 -1.00 0.67 0.67 0.00 0.33 -0.83 0.00 0.67 0.00 1.13 1.13 0.00 0.00 0.33 -1.83 -1.17 2.50 -1.00 -0.33 3.17 0.00 -1.17 2.83 1.50 -1.33 0.00 1.17 -1.33 -0.83 0.00 0.33 0.00 2.33 -0.17 0.00 1.00 0.00 1.13 1.13 -0.17 0.00 -0.33 0.67 0.67 -0.17 -0.83 1.67 -0.67 0.00 2.17 -0.17 0.17 1.17 0.00 -0.67 2.17 1.00 -0.50 -0.33 0.00 -0.83 1.17 0.00 0.50 0.00 1.13 1.13 0.67 0.00 -2.00 0.67 1.00 -1.67 0.17 -0.50 0.17 0.00 5.67 0.33 2.67 1.33 0.00 0.67 1.17 3.17 2.67 1.17 0.00 0.17 0.33 0.00 -2.83 0.00 1.13 1.13 0.33 0.00 -4.50 3.67 4.50 -5.17 0.33 2.83 -2.00 0.00 7.50 -2.33 0.67 3.00 0.00 1.50 5.50 5.83 1.00 0.67 0.00 -1.83 -0.17 0.00 -4.83 0.00 4.55 4.55 1.33 0.00 -3.50 3.83 3.67 -5.33 0.83 5.00 -2.50 0.00 6.67 -2.67 -0.67 5.33 0.00 3.67 6.00 4.83 1.33 1.17 0.00 -1.83 -2.50 0.00 -4.00 0.00 4.55 4.55 -1.17 0.00 0.17 -2.67 -1.33 5.33 -2.17 1.50 4.33 0.00 -1.83 4.83 2.17 -1.00 0.00 -1.50 -2.33 -1.50 -1.00 1.67 0.00 2.33 2.00 0.00 4.50 0.00 4.55 4.55 3.17 0.00 -3.33 12.00 9.50 -8.17 5.83 3.00 -1.83 0.00 2.83 -4.50 -3.50 5.33 0.00 1.50 4.83 0.17 4.17 2.17 0.00 -1.83 -8.67 0.00 -4.83 0.00 4.55 4.55 3.17 0.00 -2.17 6.67 6.50 -6.33 4.33 3.17 -2.17 0.00 2.83 -3.33 -2.33 5.50 0.00 4.00 5.50 1.50 4.17 1.83 0.00 -1.50 -5.83 0.00 -4.83 0.00 4.55 4.55 2.67 0.00 2.00 -0.67 -0.83 0.67 4.17 -2.83 8.67 0.00 -1.83 5.83 4.50 -1.83 0.00 1.33 -1.33 -3.00 0.17 2.33 0.00 12.83 -8.33 0.00 -1.83 0.00 4.55 4.55 4.33 0.00 3.33 2.67 2.50 -3.50 6.50 -1.50 0.17 0.00 1.50 -2.67 -1.50 2.67 0.00 3.33 -0.50 -0.67 7.50 9.17 0.00 1.00 -3.67 0.00 -3.83 0.00 4.55 4.55 0.17 0.00 -2.33 -3.17 -2.17 6.00 -2.50 -2.83 10.17 0.00 -0.83 10.50 10.00 -3.17 0.00 -1.67 -1.50 -1.50 -2.17 0.83 0.00 9.50 -3.17 0.00 0.33 0.00 4.55 4.55 -0.67 0.00 -4.67 -4.00 -2.67 10.00 -4.33 -2.33 10.33 0.00 -2.67 12.67 10.00 -3.67 0.00 -2.67 -1.67 -3.67 -3.00 0.00 0.00 9.00 1.67 0.00 2.33 0.00 4.55 4.55 -5.00 0.00 -1.00 -10.00 -6.00 15.00 -6.00 -1.00 6.00 0.00 -6.00 12.00 5.00 -5.00 0.00 -6.00 -8.00 -5.00 -3.00 -3.00 0.00 2.00 12.00 0.00 13.00 0.00 4.55 4.55 9.50 0.00 3.83 2.50 2.50 -4.00 5.67 -1.33 0.00 0.00 1.00 -2.00 -1.00 2.33 0.00 4.33 0.50 -1.33 7.50 5.50 0.00 1.00 -4.00 0.00 -3.33 0.00 4.55 4.55 3.17 0.00 -3.17 12.83 8.67 -8.83 6.00 3.00 -1.83 0.00 2.83 -4.83 -3.83 5.50 0.00 1.50 4.83 0.17 4.17 2.17 0.00 -1.83 -8.67 0.00 -4.83 0.00 4.55 4.55 0.00 0.00 2.00 -2.00 -2.00 6.00 -3.00 -3.00 15.00 0.00 -2.00 8.00 6.00 -3.00 0.00 -2.00 -3.00 -3.00 -1.00 2.00 0.00 11.00 -5.00 0.00 1.00 0.00 4.55 4.55 2.33 0.00 -0.67 2.00 3.67 -0.67 3.00 -0.67 6.67 0.00 -0.33 4.33 3.33 -0.33 0.00 1.00 0.67 -2.00 0.00 2.00 0.00 9.33 -9.00 0.00 -2.33 0.00 4.55 4.55 5.00 0.00 1.83 5.33 4.50 -5.33 11.67 -0.83 -2.67 0.00 0.33 -4.67 -3.00 5.67 0.00 2.67 1.83 -1.67 7.00 3.50 0.00 0.67 -6.67 0.00 -4.83 0.00 4.55 4.55 -3.50 0.00 0.17 -8.00 -4.67 12.00 -4.00 -1.17 4.83 0.00 -4.67 9.33 3.67 -3.67 0.00 -4.33 -6.83 -4.00 0.00 -2.00 0.00 1.50 10.50 0.00 10.17 0.00 4.55 4.55 4.00 0.00 2.67 2.00 2.00 -3.00 4.33 -1.17 1.50 0.00 2.00 -1.50 -0.50 2.17 0.00 3.17 -1.00 -0.67 5.00 13.00 0.00 1.50 -4.50 0.00 -3.17 0.00 4.55 4.55 8.67 0.00 0.50 4.00 4.83 -5.00 4.67 0.00 -0.83 0.00 3.33 -2.17 -0.50 3.00 0.00 3.50 2.50 0.00 5.17 3.17 0.00 0.17 -5.17 0.00 -4.00 0.00 4.55 4.55 -1.17 0.00 -3.17 -4.67 -3.00 9.33 -4.17 -2.33 9.67 0.00 -2.33 11.67 9.33 -3.67 0.00 -3.00 -2.67 -2.83 -2.67 -0.17 0.00 7.67 1.50 0.00 3.33 0.00 4.55 4.55 2.33 0.00 6.17 -3.50 -3.83 2.50 0.00 -0.50 -0.17 0.00 -2.50 -2.17 -3.17 -0.83 0.00 -0.83 -3.67 -0.17 5.00 0.33 0.00 -0.67 -0.50 0.00 6.50 0.00 4.55 4.55 9.33 0.00 2.50 3.83 4.67 -4.50 5.83 -0.50 -0.67 0.00 1.17 -2.33 -1.33 2.83 0.00 4.00 1.67 -1.17 7.33 3.33 0.00 0.33 -4.83 0.00 -3.67 0.00 4.55 4.55 4.33 0.00 -4.00 6.17 6.83 -6.67 3.50 4.33 -2.33 0.00 3.17 -1.83 -0.83 5.67 0.00 2.50 9.50 1.67 1.00 0.83 0.00 -1.50 -6.17 0.00 -4.50 0.00 4.55 4.55 1.83 0.00 6.00 -1.00 -1.67 -2.33 1.50 0.50 0.17 0.00 0.17 -5.17 -3.17 1.67 0.00 0.67 -1.67 0.00 3.83 1.67 0.00 0.17 -6.33 0.00 3.83 0.00 4.55 4.55 2.00 0.00 4.17 1.17 1.17 0.00 2.00 2.00 -0.00 0.00 0.50 -1.50 -1.67 2.33 0.00 1.33 -0.67 -0.17 5.00 5.33 0.00 -0.33 0.67 0.00 0.67 0.00 4.55 4.55 0.50 0.00 -1.00 1.67 2.50 -1.00 0.83 0.67 -0.33 0.00 0.50 -0.50 -0.33 0.83 0.00 0.17 1.00 0.00 0.33 0.33 0.00 -0.33 -1.83 0.00 -0.83 0.00 2.83 2.83 1.00 0.00 0.33 1.00 0.83 -1.00 2.50 -0.33 -0.50 0.00 -0.17 -0.83 -0.50 0.67 0.00 0.50 0.33 -0.50 1.00 0.67 0.00 0.33 -1.67 0.00 -1.00 0.00 2.83 2.83 8.50 0.00 1.83 2.50 2.33 -5.67 6.00 0.33 -1.50 0.00 0.33 -2.67 -1.50 1.33 0.00 9.67 2.50 0.00 4.33 3.50 0.00 1.50 -8.33 0.00 -6.00 0.00 4.55 4.55 [Part of this file has been deleted for brevity] 2.50 0.00 -1.83 3.50 2.67 -4.33 1.33 1.50 -1.17 0.00 4.33 -2.17 0.00 2.17 0.00 1.67 2.67 3.33 1.50 1.17 0.00 -0.83 -0.83 0.00 -3.33 0.00 0.27 0.27 0.50 0.00 -2.50 3.33 5.00 -2.83 1.17 2.17 -1.17 0.00 2.33 -1.67 -0.33 1.83 0.00 0.83 2.67 2.50 0.83 0.50 0.00 -1.17 -1.50 0.00 -2.67 0.00 0.27 0.27 0.50 0.00 -0.83 2.50 1.67 -1.67 1.00 0.67 -0.33 0.00 0.50 -0.83 -0.67 1.00 0.00 0.17 1.00 0.00 0.33 0.33 0.00 -0.33 -1.83 0.00 -0.83 0.00 0.27 0.27 0.50 0.00 -0.17 1.00 0.83 -1.83 2.00 0.50 -1.00 0.00 1.17 -1.50 -0.17 0.83 0.00 1.00 1.00 2.00 1.17 0.50 0.00 -0.17 0.50 0.00 -2.00 0.00 0.27 0.27 0.00 0.00 -1.00 0.50 0.50 -1.00 -0.17 0.17 -0.33 0.00 2.50 -0.50 0.33 0.67 0.00 0.17 0.67 1.33 0.33 0.33 0.00 -0.33 0.17 0.00 -1.00 0.00 0.27 0.27 0.83 0.00 -1.83 3.50 2.67 -3.00 1.33 1.67 -0.83 0.00 1.17 -1.00 -0.67 1.67 0.00 0.67 3.50 0.67 0.17 0.17 0.00 -0.67 -2.67 0.00 -1.83 0.00 0.27 0.27 -1.00 0.00 3.67 -2.00 -2.00 5.33 -2.50 0.50 2.83 0.00 -2.33 2.33 0.67 -0.83 0.00 -3.00 -2.50 -2.50 -1.50 -0.67 0.00 1.50 2.83 0.00 5.17 0.00 0.27 0.27 1.50 0.00 -2.83 5.83 6.67 -3.67 2.67 2.00 -1.00 0.00 1.50 -1.83 -1.33 2.67 0.00 0.50 3.00 0.00 1.00 1.00 0.00 -1.00 -5.50 0.00 -2.50 0.00 0.27 0.27 0.67 0.00 -0.33 -1.33 -1.00 1.50 0.17 -1.50 4.67 0.00 -0.33 4.67 4.50 -1.50 0.00 0.00 -0.67 -0.67 -0.83 0.67 0.00 6.00 -3.17 0.00 -0.50 0.00 0.27 0.27 1.67 0.00 -1.67 3.67 5.33 -2.50 2.33 1.17 -0.33 0.00 1.33 -1.17 -0.67 2.00 0.00 0.83 1.83 -0.17 1.17 3.17 0.00 -0.33 -4.67 0.00 -2.17 0.00 0.27 0.27 3.83 0.00 -0.17 3.17 2.33 -3.50 2.50 0.83 -0.67 0.00 0.67 -1.50 -1.00 1.33 0.00 3.50 1.83 0.00 1.67 1.50 0.00 0.17 -4.50 0.00 -2.67 0.00 0.27 0.27 1.83 0.00 -0.67 1.17 1.17 0.00 4.17 -1.00 0.33 0.00 -0.83 0.83 1.00 0.67 0.00 0.50 0.50 -1.67 1.33 1.17 0.00 2.00 -2.50 0.00 -1.50 0.00 0.27 0.27 0.50 0.00 1.50 -0.33 -0.50 -1.17 0.17 0.00 0.00 0.00 1.50 -1.83 -0.67 0.17 0.00 0.33 -0.33 0.83 1.33 0.67 0.00 0.00 -1.83 0.00 0.67 0.00 0.27 0.27 2.33 0.00 1.00 1.67 1.33 -1.67 5.33 -1.17 0.83 0.00 -0.67 -0.33 0.00 0.83 0.00 1.17 0.33 -1.50 1.83 1.67 0.00 3.17 -4.67 0.00 -2.17 0.00 0.27 0.27 2.17 0.00 -0.17 3.83 2.83 -3.17 4.17 0.17 -0.50 0.00 0.67 -1.83 -1.17 2.00 0.00 1.17 1.17 -0.67 1.83 3.50 0.00 0.33 -4.50 0.00 -2.33 0.00 0.27 0.27 1.00 0.00 -2.00 3.33 5.00 -2.00 1.67 1.33 -0.67 0.00 1.00 -1.00 -0.67 1.67 0.00 0.33 2.00 0.00 0.67 0.67 0.00 -0.67 -3.67 0.00 -1.67 0.00 0.27 0.27 -0.67 0.00 -0.67 -0.33 -0.33 -1.33 -0.67 1.17 0.83 0.00 2.33 0.00 1.67 -0.17 0.00 1.17 1.00 4.50 0.17 0.00 0.00 1.50 3.00 0.00 -2.17 0.00 0.27 0.27 3.17 0.00 0.33 1.17 1.00 -1.33 2.00 0.17 1.33 0.00 0.33 0.50 0.50 2.33 0.00 1.00 0.67 -0.83 1.00 1.33 0.00 2.33 -3.17 0.00 -0.83 0.00 0.27 0.27 0.83 0.00 -1.00 0.17 0.33 1.00 1.67 -0.67 0.83 0.00 -0.67 1.67 1.50 0.00 0.00 0.00 0.17 -1.17 0.33 0.50 0.00 1.67 -0.83 0.00 -0.50 0.00 0.27 0.27 2.33 0.00 -1.00 1.50 1.50 -3.00 0.83 1.67 -1.00 0.00 2.00 -1.00 0.33 1.17 0.00 1.83 3.50 2.67 0.67 0.33 0.00 -0.50 0.00 0.00 -2.50 0.00 0.27 0.27 1.17 0.00 3.00 0.50 0.33 0.67 2.50 -0.17 -0.50 0.00 -0.83 -1.00 -1.17 1.00 0.00 -0.17 -0.83 -1.33 2.83 0.67 0.00 0.00 0.67 0.00 0.83 0.00 0.27 0.27 2.33 0.00 -0.83 -0.33 0.00 1.17 0.17 -0.50 1.33 0.00 -0.50 2.33 2.00 -0.33 0.00 0.33 0.17 -1.17 0.00 0.50 0.00 1.67 -0.50 0.00 0.00 0.00 0.27 0.27 0.67 0.00 -0.33 -0.17 -0.17 -0.33 0.50 -0.83 3.33 0.00 1.83 2.17 2.33 -0.33 0.00 0.50 0.00 0.33 0.00 1.00 0.00 4.67 -2.50 0.00 -1.33 0.00 0.27 0.27 3.67 0.00 0.50 2.50 3.33 -2.33 2.83 0.17 -0.50 0.00 0.83 -1.33 -0.83 1.67 0.00 1.67 1.17 -0.33 3.50 1.50 0.00 -0.17 -2.67 0.00 -2.00 0.00 0.27 0.27 0.83 0.00 -1.83 5.67 4.00 -3.50 1.67 3.83 -1.17 0.00 1.17 -2.00 -1.83 2.83 0.00 0.67 3.00 0.83 0.33 0.50 0.00 -1.17 -3.83 0.00 -1.17 0.00 0.27 0.27 1.83 0.00 0.17 1.50 1.50 -2.83 1.83 1.00 -1.00 0.00 1.17 -1.33 -0.83 1.17 0.00 3.67 2.83 1.33 3.00 0.83 0.00 -0.33 -1.67 0.00 -3.00 0.00 0.27 0.27 0.17 0.00 -0.67 -1.50 -1.17 3.33 -1.00 -1.33 5.67 0.00 -1.17 5.17 4.00 -1.67 0.00 -0.67 -1.00 -1.67 -1.00 0.50 0.00 5.67 -1.33 0.00 0.50 0.00 0.27 0.27 0.50 0.00 -3.00 2.67 3.50 -3.00 0.50 1.00 -1.00 0.00 5.50 -1.50 0.33 2.17 0.00 0.50 2.33 2.67 1.00 1.00 0.00 -1.00 -1.50 0.00 -2.83 0.00 0.27 0.27 1.67 0.00 -0.33 0.67 0.83 -0.67 2.67 -1.00 0.83 0.00 0.50 1.00 2.00 0.50 0.00 0.67 0.17 -0.33 1.00 3.17 0.00 1.67 -3.17 0.00 -1.67 0.00 0.27 0.27 -1.50 0.00 0.17 -3.33 -2.33 6.67 -2.83 0.00 2.50 0.00 -2.50 5.00 2.67 -1.67 0.00 -2.83 -2.50 -2.50 -1.83 -1.17 0.00 1.50 4.67 0.00 5.17 0.00 0.27 0.27 0.17 0.00 -3.33 0.67 1.00 -0.33 -0.67 0.83 0.50 0.00 2.67 1.83 2.33 0.67 0.00 0.17 3.00 1.33 -0.50 0.00 0.00 0.67 0.17 0.00 -1.50 0.00 0.27 0.27 0.50 0.00 -0.67 -0.83 -0.50 2.50 -0.67 -1.00 4.17 0.00 -0.50 3.67 3.00 -0.83 0.00 -0.33 -0.83 -1.33 -0.33 2.67 0.00 3.50 -1.00 0.00 0.17 0.00 0.27 0.27 -0.33 0.00 -0.17 -0.67 -0.50 3.33 -1.17 1.00 1.00 0.00 -0.83 2.33 1.33 1.67 0.00 -1.83 -0.50 -1.50 -0.83 -0.33 0.00 0.67 2.17 0.00 2.83 0.00 0.27 0.27 0.50 0.00 -1.00 -0.50 -0.17 1.50 -0.17 -0.50 1.67 0.00 -0.17 2.33 2.00 -0.33 0.00 0.00 -0.33 -0.83 -0.17 2.33 0.00 1.67 -0.17 0.00 0.00 0.00 0.27 0.27 0.33 0.00 0.67 -0.67 -0.67 1.33 -0.17 -1.00 4.33 0.00 -0.67 2.67 2.00 -1.00 0.00 -0.17 -0.83 -1.00 -0.33 0.67 0.00 4.33 -2.17 0.00 0.00 0.00 0.27 0.27 0.83 0.00 0.17 0.17 0.17 -1.00 0.50 0.33 -0.33 0.00 0.17 -0.50 -0.33 0.00 0.00 2.50 0.50 0.50 0.67 0.50 0.00 0.17 -1.33 0.00 -1.33 0.00 0.27 0.27 0.67 0.00 1.00 0.33 0.33 -0.50 1.00 -0.33 -0.17 0.00 0.33 -0.67 -0.50 0.50 0.00 0.67 -0.17 0.17 2.50 0.50 0.00 -0.17 0.50 0.00 -0.67 0.00 0.27 0.27 -0.50 0.00 -0.50 0.00 0.00 -0.83 -0.50 0.83 -0.50 0.00 1.33 -0.67 0.33 0.17 0.00 0.50 0.67 2.50 0.17 -0.17 0.00 -0.50 2.17 0.00 -1.00 0.00 0.27 0.27 0.33 0.00 -0.50 1.00 0.83 -0.83 0.67 0.83 -0.50 0.00 0.67 -0.67 -0.50 2.50 0.00 0.00 0.67 0.17 0.50 0.33 0.00 -0.50 -0.50 0.00 -0.17 0.00 0.27 0.27 -0.83 0.00 -0.17 -1.67 -1.00 2.50 -1.00 -0.17 1.00 0.00 -1.00 2.00 0.83 -0.83 0.00 -1.00 -1.33 -0.83 -0.50 -0.50 0.00 0.33 2.00 0.00 2.17 0.00 0.27 0.27 2.50 0.00 0.50 0.50 0.50 -0.83 1.00 -0.17 0.00 0.00 0.00 -0.17 0.00 0.33 0.00 0.83 0.33 -0.50 0.67 0.67 0.00 0.33 -1.33 0.00 -0.50 0.00 0.27 0.27 2.50 0.00 0.50 0.50 0.50 -0.83 1.00 -0.17 0.00 0.00 0.00 -0.17 0.00 0.33 0.00 0.83 0.33 -0.50 0.67 0.67 0.00 0.33 -1.33 0.00 -0.50 0.00 0.27 0.27 -0.17 0.00 -1.33 -0.83 -0.50 2.00 -0.83 -0.33 1.33 0.00 -0.50 2.50 2.00 -0.67 0.00 -0.50 -0.17 -0.67 -0.67 -0.17 0.00 1.33 0.83 0.00 0.50 0.00 0.27 0.27 -0.50 0.00 -0.50 0.00 0.00 -0.83 -0.50 0.83 -0.50 0.00 1.33 -0.67 0.33 0.17 0.00 0.50 0.67 2.50 0.17 -0.17 0.00 -0.50 2.17 0.00 -1.00 0.00 0.27 0.27 -0.17 0.00 -1.33 -0.83 -0.50 2.00 -0.83 -0.33 1.33 0.00 -0.50 2.50 2.00 -0.67 0.00 -0.50 -0.17 -0.67 -0.67 -0.17 0.00 1.33 0.83 0.00 0.50 0.00 0.27 0.27 0.50 0.00 -0.83 2.50 1.67 -1.67 1.00 0.67 -0.33 0.00 0.50 -0.83 -0.67 1.00 0.00 0.17 1.00 0.00 0.33 0.33 0.00 -0.33 -1.83 0.00 -0.83 0.00 0.27 0.27 -0.50 0.00 -0.50 0.00 0.00 -0.83 -0.50 0.83 -0.50 0.00 1.33 -0.67 0.33 0.17 0.00 0.50 0.67 2.50 0.17 -0.17 0.00 -0.50 2.17 0.00 -1.00 0.00 0.27 0.27 0.50 0.00 -1.00 1.67 2.50 -1.00 0.83 0.67 -0.33 0.00 0.50 -0.50 -0.33 0.83 0.00 0.17 1.00 0.00 0.33 0.33 0.00 -0.33 -1.83 0.00 -0.83 0.00 0.27 0.27 -0.50 0.00 1.67 -0.83 -0.83 2.17 -1.00 0.50 0.17 0.00 -1.00 0.50 -0.17 -0.17 0.00 -1.33 -1.00 -1.00 -0.67 -0.50 0.00 -0.17 1.83 0.00 2.50 0.00 0.27 0.27 -0.83 0.00 -0.17 -1.67 -1.00 2.50 -1.00 -0.17 1.00 0.00 -1.00 2.00 0.83 -0.83 0.00 -1.00 -1.33 -0.83 -0.50 -0.50 0.00 0.33 2.00 0.00 2.17 0.00 0.27 0.27 0.50 0.00 -0.83 2.50 1.67 -1.67 1.00 0.67 -0.33 0.00 0.50 -0.83 -0.67 1.00 0.00 0.17 1.00 0.00 0.33 0.33 0.00 -0.33 -1.83 0.00 -0.83 0.00 0.27 0.27 |
Standard (Mandatory) qualifiers (* if not always prompted): [-dafinpath] dirlist This option specifies the location of DAF files (domain alignment files) (input). A 'domain alignment file' contains a sequence alignment of domains belonging to the same SCOP or CATH family. The file is in clustal format annotated with domain family classification information. The files generated by using SCOPALIGN will contain a structure-based sequence alignment of domains of known structure only. Such alignments can be extended with sequence relatives (of unknown structure) by using SEQALIGN. -matrixfile matrixf This option specifies the residue substitution matrix. Epprofile for Gribskov profiles or EBLOSUM62 otherwise. -mode menu This option specifies the mode of LIBGEN operation. LIBGEN generates one of six types of profile for each alignment. Supported profiles include simple frequency matrices, Gribskov profiles, Hennikoff profiles, hidden Markov models (HMMER package), hidden Markov models (SAM-T2K package) and position-specific scoring matrices. * -threshold integer This option specifies the threshold reporting percentage. The threshold reporting percentage is used in the construction of the simple frequency matrix. * -gapopen float This option specifies the gap insertion penalty. The gap insertion penalty is the score taken away when a gap is created. The best value depends on the choice of comparison matrix. The default value assumes you are using the EBLOSUM62 matrix for protein sequences, and the EDNAFULL matrix for nucleotide sequences. * -gapextend float This option specifies the gap extension penalty. The gap extension, penalty is added to the standard gap penalty for each base or residue in the gap. This is how long gaps are penalized. Usually you will expect a few long gaps rather than many short gaps, so the gap extension penalty should be lower than the gap penalty. An exception is where one or both sequences are single reads with possible sequencing errors in which case you would expect many single base gaps. You can get this result by setting the gap open penalty to zero (or very low) and using the gap extension penalty to control gap scoring. [-outdir] outdir This option specifies the location of discriminator files (output). The discriminator files contain one of the supported profiles, including simple frequency matrices, Gribskov profiles, Hennikoff profiles, hidden Markov models (HMMER package), hidden Markov models (SAM-T2K package) and position-specific scoring matrices. Additional (Optional) qualifiers: (none) Advanced (Unprompted) qualifiers: (none) Associated qualifiers: (none) General qualifiers: -auto boolean Turn off prompts -stdout boolean Write standard output -filter boolean Read standard input, write standard output -options boolean Prompt for standard and additional values -debug boolean Write debug output to program.dbg -verbose boolean Report some/full command line options -help boolean Report command line options. More information on associated and general qualifiers can be found with -help -verbose -warning boolean Report warnings -error boolean Report errors -fatal boolean Report fatal errors -die boolean Report deaths
Standard (Mandatory) qualifiers | Allowed values | Default | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
[-dafinpath] (Parameter 1) |
This option specifies the location of DAF files (domain alignment files) (input). A 'domain alignment file' contains a sequence alignment of domains belonging to the same SCOP or CATH family. The file is in clustal format annotated with domain family classification information. The files generated by using SCOPALIGN will contain a structure-based sequence alignment of domains of known structure only. Such alignments can be extended with sequence relatives (of unknown structure) by using SEQALIGN. | Directory with files | ./ | ||||||||||||
-matrixfile | This option specifies the residue substitution matrix. Epprofile for Gribskov profiles or EBLOSUM62 otherwise. | Comparison matrix file in EMBOSS data path | Epprofile for Gribskov type, or EBLOSUM62 | ||||||||||||
-mode | This option specifies the mode of LIBGEN operation. LIBGEN generates one of six types of profile for each alignment. Supported profiles include simple frequency matrices, Gribskov profiles, Hennikoff profiles, hidden Markov models (HMMER package), hidden Markov models (SAM-T2K package) and position-specific scoring matrices. |
|
1 | ||||||||||||
-threshold | This option specifies the threshold reporting percentage. The threshold reporting percentage is used in the construction of the simple frequency matrix. | Integer from 1 to 100 | 75 | ||||||||||||
-gapopen | This option specifies the gap insertion penalty. The gap insertion penalty is the score taken away when a gap is created. The best value depends on the choice of comparison matrix. The default value assumes you are using the EBLOSUM62 matrix for protein sequences, and the EDNAFULL matrix for nucleotide sequences. | Any numeric value | 3.0 | ||||||||||||
-gapextend | This option specifies the gap extension penalty. The gap extension, penalty is added to the standard gap penalty for each base or residue in the gap. This is how long gaps are penalized. Usually you will expect a few long gaps rather than many short gaps, so the gap extension penalty should be lower than the gap penalty. An exception is where one or both sequences are single reads with possible sequencing errors in which case you would expect many single base gaps. You can get this result by setting the gap open penalty to zero (or very low) and using the gap extension penalty to control gap scoring. | Any numeric value | 0.3 | ||||||||||||
[-outdir] (Parameter 2) |
This option specifies the location of discriminator files (output). The discriminator files contain one of the supported profiles, including simple frequency matrices, Gribskov profiles, Hennikoff profiles, hidden Markov models (HMMER package), hidden Markov models (SAM-T2K package) and position-specific scoring matrices. | Output directory | ./ | ||||||||||||
Additional (Optional) qualifiers | Allowed values | Default | |||||||||||||
(none) | |||||||||||||||
Advanced (Unprompted) qualifiers | Allowed values | Default | |||||||||||||
(none) |
% libgen Generates various types of discriminating elements for each alignment in a directory. Location of DAF files (domain alignment files) (input). [./]: structure Residue substitution matrix. [EBLOSUM62]: EBLOSUM62 Discrimininator type 1 : Simple frequency matrix 2 : Gribskov profile 3 : Henikoff profile 4 : Hidden Markov model (HMMER) 5 : Hidden Markov model (SAM-T2K) 6 : Position-specific scoring matrix Select type. [1]: 2 Location of discriminator files (output). [./]: |
Go to the output files for this example
Domain alignment files of file extension .salign (specified in ACD)
were read from /test_data. A Gribskov profile was generated and
written to /test_data/libgen. The EBLOSUM62 residue substitution
matrix was used.
FILE TYPE | FORMAT | DESCRIPTION | CREATED BY | SEE ALSO |
Domain alignment file | DAF format (CLUSTAL-like format with domain classification information). | Contains a sequence alignment of domains belonging to the same SCOP or CATH family. The file is annotated with domain family classification information. | DOMAINALIGN (structure-based sequence alignment of domains of known structure). | DOMAINALIGN alignments can be extended with sequence relatives (of unknown structure) to the family in question by using SEQALIGN. |
Hidden Markov models | A file containing a hidden Markov model. | Can be generated for SCOP or CATH families by using LIBGEN which uses the HMMER & SAM-T2K packages. | N.A. | |
Simple frequency matrices, Gribskov profiles, Hennikoff profiles & position-specific scoring matrices | A file containing a simple frequency matrix, Gribskov profile, Hennikoff profile or position-specific scoring matrix. | Can be generated for SCOP or CATH families by using LIBGEN, which uses the BLAST package. | N.A. |
Program name | Description |
---|---|
contactcount | Counts specific versus non-specific contacts in a directory of cleaned protein chain contact files |
contacts | Reads CCF files (clean coordinate files) and writes CON files (contact files) of intra-chain residue-residue contact data |
domainalign | Generates DAF files (domain alignment files) of structure-based sequence alignments for nodes in a DCF file (domain classification file) |
domainrep | Reorder DCF file (domain classification file) so that the representative structure of each user-specified node is given first |
domainreso | Removes low resolution domains from a DCF file (domain classification file) |
interface | Reads CCF files (clean coordinate files) and writes CON files (contact files) of inter-chain residue-residue contact data |
psiphi | Calculates phi and psi torsion angles from cleaned EMBOSS-style protein co-ordinate file |
rocon | Reads a DHF file (domain hits file) of hits (sequences of unknown structural classification) and a DHF file of validation sequences (known classification) and writes a 'hits file' for the hits, which are classified and rank-ordered on the basis of score |
rocplot | Provides interpretation and graphical display of the performance of discriminating elements (e.g. profiles for protein families). rocplot reads file(s) of hits from discriminator-database search(es), performs ROC analysis on the hits, and writes graphs illustrating the diagnostic performance of the discriminating elements |
seqalign | Reads a DAF file (domain alignment file) and a DHF file (domain hits file) and writes a DAF file extended with the hits |
seqfraggle | Removes fragments from DHF files (domain hits files) or other files of sequences |
seqsearch | Generate database hits (sequences) for nodes in a DCF file (domain classification file) by using PSI-BLAST |
seqsort | Reads DHF files (domain hits files) of database hits (sequences) and removes hits of ambiguous classification |
seqwords | Generates DHF files (domain hits files) of database hits (sequences) for nodes in a DCF file (domain classification file) by keyword search of UniProt |
siggen | Generates a sparse protein signature from an alignment and residue contact data |
sigscan | Generates a DHF file (domain hits file) of hits (sequences) from scanning a signature against a sequence database |
See also http://emboss.sourceforge.net/